Main TopicsWhich is the most widely used column in SFC?
Table of Contents
Which is the most widely used column in SFC?
Most SFCs currently are involved a silica (or silica + modifier) packed column with a CO2 (or CO2 + modifier) mobile phase. Mass spectrometry is the most common tool used to analyze the separated samples.
What is the purpose of flow restrictor in supercritical chromatography?
Supercritical Fluid Chromatographic Detection by use of a Parallel Flow Restrictor. In supercritical fluid chromatography (SFC), the role of the flow restrictor is not only to maintain supercritical conditions throughout the column but also to provide the necessary interface between the column and the detector.
What are the phases of the SFC column?
These phases are based on a new patent-pending two-stage functionalization of ethylene bridged hybrid (BEH) particles.
Why do you need a column oven in SFC?
Column Oven and Heating: In SFC, pressure and temperature are method parameters that impact the separation because they affect mobile phase density. As a result, proper heating and temperature control of the mobile phase and column are necessary.
Which is the most commonly used SFC tool?
Most SFCs currently are involved a silica (or silica + modifier) packed column with a CO 2 (or CO 2 + modifier) mobile phase. Mass spectrometry is the most common tool used to analyze the separated samples. What is a Supercritical Fluid?
Why are trefoil columns used in SFC chromatography?
The preparative format utilizes our patented OBD Technology to ensure ease of scale-up as well as column-to-column consistency. Trefoil Columns, for chiral SFC chromatography, are uniquely designed for the ACQUITY UPC 2 System for selectivity and speed in separations as well as reduced method development time.
